Electrode Position and Current Amplitude Modulate Impulsivity after Subthalamic Stimulation in Parkinsons Disease—A Computational Study
نویسندگان
چکیده
منابع مشابه
Electrode Position and Current Amplitude Modulate Impulsivity after Subthalamic Stimulation in Parkinsons Disease—A Computational Study
Background: Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) is highly effective in alleviating motor symptoms of Parkinson's disease (PD) which are not optimally controlled by dopamine replacement therapy. Clinical studies and reports suggest that STN-DBS may result in increased impulsivity and de novo impulse control disorders (ICD). Objective/Hypothesis: We aimed to compare performance o...
متن کاملElectrode Position and the Clinical Outcome after Bilateral Subthalamic Nucleus Stimulation
We compared the surgical outcome with electrode positions after bilateral subthalamic nucleus (STN) stimulation surgery for Parkinson's disease. Fifty-seven patients treated with bilateral STN stimulations were included in this study. Electrode positions were determined in the fused images of preoperative MRI and postoperative CT taken at six months after surgery. The patients were divided into...
متن کاملOptimization of electrode position and electric pulse amplitude in electrochemotherapy
Electrochemotherapy (ECT) is an effective local tumor therapy performed by the administration of chemotherapeutic drugs followed by the application of local high-voltage electric pulses.1, 2 The electric pulses cause transient structural changes (electroporation) of tumor cell membranes and thus increase the entrance of the chemotherapeutic drugs. This potentiates the chemotherapeutic effect an...
متن کاملDeep Brain Stimulation of the Subthalamic Nucleus Improves Lexical Switching in Parkinsons Disease Patients
OBJECTIVE Reduced verbal fluency (VF) has been reported in patients with Parkinson's disease (PD), especially those treated by Deep Brain Stimulation of the subthalamic nucleus (STN DBS). To delineate the nature of this dysfunction we aimed at identifying the particular VF-related operations modified by STN DBS. METHOD Eleven PD patients performed VF tasks in their STN DBS ON and OFF conditio...
متن کاملSurface electrode position during ulnar nerve stimulation.
who had a mean PCV of 49.4% with a control group who had a mean PCV of 42.1 %. The mean TEI in the first group was 31.25 £2, which was significantly greater than that in the second group—27.5 n (P < 0.05) [5]. These observations may help to explain the "surprisingly increased response in TEI" noted by the authors. The influence of PCV clearly assumes greater importance with larger variations in...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2016
ISSN: 1664-042X
DOI: 10.3389/fphys.2016.00585